Journal of Ethnopharmacology - ۱۹۹۱

In mice, an extract of Crocus sativus stigmas partially prevented the decreases in body weight, hemoglobin levels and leucocyte counts caused by ۲ mg/kg of cisplatin i.p. for ۵ days. Treatment with the C. sativus extract also significantly prolonged the life span of cisplatin-treated mice almost three-fold. In contrast, an extract of Nigella saliva seed only tended to protect from cisplatin-induced falls in hemoglobin levels and leucocyte counts